人類的脊柱由33-34塊脊椎骨(拉丁語:Vertebrae)和中間起緩衝作用的椎間盤組成。這個結構通過韌帶和小的脊柱關節固定。
脊柱人為劃分為7頸椎、12胸椎、5腰椎、骶骨和尾骨(這種分類對所有哺乳類動物有效,從老鼠到長頸鹿)。人類的5塊骶骨和4塊尾骨相互融合,它們被稱之為「假脊椎」。有尾巴的脊椎動物有數目不等的尾骨。
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